Recently, Shandong Dezhou University Shandong Provincial Key Laboratory of Biophysical Research team made significant progress in graphene biosensing technology research and development, made a major research achievement for the world. It is reported that graphene has been honored as the advanced material of "changing the 21st century" because of its many excellent qualities of mechanics, optics, electricity and micro-quantum. Existing research shows that graphene-related human health and biomedical applications bright prospects. Over the years, Dr. Xu Shi-cai, Professor Wang Jihua and Professor Zhou Yaqi led the research team to conduct a painstaking research on graphene biosensing technology. From September 2014 to December 2016, the team conducted intensive research in this area and successively solved the problems of controllable growth of centimeter grade single crystal graphene, nondestructive modification of probe molecules and sensor analysis model, finally mastered The key technology of graphene biosensing has solved the worldwide technical problems that graphene biosensors currently face and has completely independent intellectual property rights. It is understood that, due to the graphene biosensor is an electrical analyzer, small size, manufacturing costs are very low, with very attractive market value, the market prospects. At present, biosensors and graphene materials involved in the ultra-trace single-crystal graphene biosensing technology are included in the national strategic emerging industry development plan for the "Thirteenth Five-year Plan" and in line with the "10 + 6" dominant industry layout of Dezhou .