Abstract: The chemical industry occupies an important position in the social and economic development. However, due to the particularity of its production activities, the environment is also harmed by the chemical industry. Under the concept of low-carbon economy development, in order to achieve the coordinated development of economy and environmental protection, we must proceed from the actual situation and combine the production characteristics of chemical enterprises to study their exhaust gas treatment processes to enhance the comprehensive treatment effect of exhaust gas, especially VOCs, Environmental impact. This article has carried on the brief analysis to the chemical enterprise exhaust gas comprehensive management engineering design.